Are you ready to experience the perfect blend of cheesy goodness and hearty flavors? Our Mac and Cheese Meatloaf Casserole is a delicious twist on two beloved comfort foods: classic macaroni and cheese combined with savory meatloaf. Whether you’re cooking for a family dinner, a gathering with friends, or just craving something indulgent, this recipe is guaranteed to be a hit! Read on to discover everything you need to know to make this irresistible dish, including ingredient details, variations, and tips for perfect results.

What is Mac and Cheese Meatloaf Casserole?
Mac and Cheese Meatloaf Casserole is a fusion recipe that combines the creamy, cheesy texture of macaroni and cheese with the rich, seasoned flavor of meatloaf. The two components are layered together to create a mouthwatering casserole that's baked to perfection. The top is often garnished with more cheese or breadcrumbs for an added crunch, resulting in a dish that’s both comforting and satisfying. It’s easy to make, versatile, and a true crowd-pleaser!
Ingredients List for Mac and Cheese
To prepare the macaroni and cheese layer, you’ll need the following ingredients:
- 2 cups elbow macaroni (uncooked)
- 2 tablespoons butter
- 2 tablespoons all-purpose flour
- 2 cups milk (whole milk works best)
- 2 cups shredded cheddar cheese
- Salt and pepper to taste
- ½ teaspoon mustard powder (optional, for added flavor)
- ¼ cup grated Parmesan cheese (optional, for extra cheesiness)
Ingredients List for Meatloaf
For the meatloaf layer, gather these ingredients:
- 1 ½ pounds ground beef (80% lean recommended)
- ½ cup breadcrumbs (plain or seasoned)
- ¼ cup milk (to keep the meatloaf moist)
- ½ cup chopped onion
- 2 cloves garlic (minced)
- 1 large egg
- 2 tablespoons Worcestershire sauce
- ½ cup ketchup (plus extra for topping)
- Salt and pepper to taste
- ¼ teaspoon dried thyme (optional, for extra flavor)
Substitutions and Variations
- Ground Meat Options: Swap the ground beef with ground turkey, chicken, or even a plant-based meat substitute for a different flavor profile.
- Cheese Choices: Experiment with different cheeses like mozzarella, gouda, or pepper jack for a unique twist on the classic mac and cheese.
- Low-Carb Option: Use cauliflower rice instead of macaroni to make a low-carb version of this casserole.
- Add Veggies: Include finely diced bell peppers, mushrooms, or spinach to pack in some extra nutrients.
Step-by-Step Cooking Instructions

How to Prepare the Mac and Cheese Layer
- Cook the pasta: Boil the elbow macaroni in salted water according to the package instructions until al dente. Drain and set aside.
- Make the cheese sauce: In a medium saucepan, melt the butter over medium heat. Stir in the flour and cook for 1-2 minutes to form a roux.
- Add the milk: Gradually whisk in the milk, making sure to break up any lumps. Continue to cook until the mixture thickens slightly.
- Add the cheese: Stir in the shredded cheddar cheese and Parmesan (if using). Season with salt, pepper, and mustard powder. Stir until the cheese is fully melted and the sauce is smooth.
- Combine with pasta: Mix the cheese sauce with the cooked macaroni. Set aside.
How to Prepare the Meatloaf Layer
- Mix the meat: In a large bowl, combine the ground beef, breadcrumbs, milk, chopped onion, garlic, egg, Worcestershire sauce, and ketchup. Season with salt, pepper, and thyme.
- Combine ingredients: Use your hands to mix all the ingredients until well combined, being careful not to over-mix to keep the meatloaf tender.
How to Cook Mac and Cheese Meatloaf Casserole: A Step-by-Step Guide
Step 1: Assemble the Casserole
- Preheat the oven: Preheat your oven to 350°F (175°C).
- Layer the meatloaf: Spread the meatloaf mixture evenly at the bottom of a greased 9x13-inch baking dish.
- Top with mac and cheese: Spoon the mac and cheese over the meatloaf layer, spreading it out evenly.
- Add toppings: For extra flavor, sprinkle more shredded cheese or breadcrumbs on top.
Step 2: Bake
- Bake the casserole: Place the dish in the preheated oven and bake for about 40-45 minutes or until the meatloaf is cooked through (internal temperature should reach 160°F) and the top is golden brown.
- Rest before serving: Allow the casserole to rest for about 10 minutes before serving to help it set and make it easier to slice.
Common Mistakes to Avoid
- Overcooking the Macaroni: Make sure to cook the pasta to just al dente so that it doesn’t become mushy after baking.
- Not Draining Excess Fat: If using a high-fat ground beef, consider draining some fat from the meatloaf layer before adding the mac and cheese on top.
- Uneven Layering: Spread each layer evenly to ensure that every bite has the perfect balance of meatloaf and mac and cheese.
Serving and Presentation Tips
How to Serve Mac and Cheese Meatloaf Casserole
- Portion Sizes: Cut the casserole into square or rectangular portions for easy serving.
- Accompaniments: Serve with a fresh green salad, steamed vegetables, or garlic bread for a complete meal.
Presentation Ideas for Mac and Cheese Meatloaf Casserole
- Herb Garnish: Add a sprinkle of fresh parsley or chives on top for a pop of color.
- Extra Cheese: Grate a little more cheese on top before the final baking stage for a gooey, cheesy finish.
- Individual Servings: For a fun twist, use muffin tins to create mini mac and cheese meatloaf bites—perfect for parties or portion control!
Mac and Cheese Meatloaf Casserole Recipe Tips
- Use Fresh Cheese: Grate your own cheese instead of using pre-shredded varieties for the best melting texture.
- Season Well: Don’t skimp on the seasonings, especially in the meatloaf layer. The right blend of herbs and spices brings out the best flavors.
- Rest Before Slicing: Let the casserole sit for a few minutes after baking to firm up, which will make serving easier and less messy.
Frequently Asked Questions (FAQs)
1. Can I make this casserole ahead of time? Yes, you can prepare the meatloaf and mac and cheese layers separately, then assemble them in the baking dish. Cover and refrigerate for up to 24 hours. When you’re ready to bake, allow it to come to room temperature and bake as directed.
2. Can I freeze Mac and Cheese Meatloaf Casserole? Absolutely! Once cooled, cover the casserole tightly with plastic wrap and aluminum foil. It can be frozen for up to 3 months. Thaw overnight in the refrigerator before reheating.
3. How do I reheat leftovers without drying them out? Cover the leftovers with foil and reheat in the oven at 350°F until warmed through. You can also add a splash of milk to the mac and cheese layer to restore its creaminess.
4. Can I use gluten-free pasta and breadcrumbs? Yes, you can easily make this dish gluten-free by substituting with gluten-free pasta and breadcrumbs.
5. What’s the best way to store leftovers? Store any leftover casserole in an airtight container in the refrigerator for up to 3-4 days.
Conclusion
Mac and Cheese Meatloaf Casserole is a delightful combination of two classic comfort foods that promises to become a family favorite. With its creamy cheese sauce, tender meatloaf, and satisfying layers, this dish is perfect for any occasion. By following the tips, substitutions, and step-by-step instructions, you’ll be well on your way to creating a delicious meal that’s sure to impress. So go ahead, gather your ingredients, and treat yourself to this ultimate comfort food today!
PrintMac and Cheese Meatloaf Casserole Recipe
This Mac and Cheese Meatloaf Casserole recipe is the ultimate comfort food, combining creamy macaroni and cheese with savory meatloaf in one delicious dish. Perfect for family dinners, this hearty casserole is a crowd-pleaser that's easy to prepare and sure to satisfy. Keywords: mac and cheese meatloaf casserole, comfort food, easy dinner recipes.
- Prep Time: 20 minutes
- Cook Time: 45 minutes
- Total Time: 65 minutes
- Yield: 6 servings 1x
- Category: Main Course
- Method: Baking
- Cuisine: American
- Diet: Gluten Free
Ingredients
- 1 lb ground beef
- 1 cup bread crumbs
- 1 egg
- ½ cup onion, diced
- 2 cups macaroni pasta
- 2 cups shredded cheddar cheese
- ½ cup milk
- 2 cups marinara sauce
- Salt and pepper to taste
Instructions
- Preheat oven to 375°F (190°C).
- Cook macaroni according to package instructions, then drain and set aside.
- In a bowl, combine ground beef, bread crumbs, egg, onion, salt, and pepper. Mix well.
- Press the meat mixture into the bottom of a greased casserole dish.
- Bake the meat layer for 15-20 minutes, until lightly browned.
- Spread marinara sauce evenly over the cooked meat layer.
- In a separate bowl, mix cooked macaroni, shredded cheese, and milk.
- Layer the macaroni and cheese mixture on top of the meat and marinara.
- Bake for another 20-25 minutes, or until the cheese is melted and bubbly.
- Let it cool for 5 minutes before serving.
Notes
- You can substitute ground beef with turkey or chicken for a lighter version.
- Use any type of pasta you prefer, though elbow macaroni works best.
- Adjust cheese quantity according to taste.
Nutrition
- Serving Size: 1 slice
- Calories: 450
- Sugar: 6g
- Sodium: 850mg
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